Significant Increase in Functional Dyspepsia Since the Pandemic

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This article was originally written on August 8, 2025, and was updated on April 21, 2026.

Introduction

Functional Dyspepsia is a disorder similar to Irritable Bowel Syndrome (IBS), which affects the stomach rather than the bowel, and just like IBS, it is diagnosed after ruling out underlying structural or biochemical causes such as peptic ulcers, gastritis, or Gastro-Esophageal Reflux Disorder (GERD).

Symptoms of Functional Dyspepsia may include pain or burning called epigastric pain syndrome (EPS), getting full quickly when eating, and/or feeling excessively full after eating called postprandial distress syndrome (PDS), feeling bloated, or experiencing reflux. Significantly, not all individuals have the same symptoms.

Practitioner’s Preface

In my almost 18 years of private clinical practice and my licensure in British Columbia, Alberta, and Ontario, I have come across only a few cases of functional dyspepsia, and have noticed many more cases over the last 5 years.  I didn’t know if this was only something I observed until I saw this 2025 study [1].

Functional Dyspepsia and IBS Surge After the Pandemic

A recent study [1] of over 4000 adults in both the US and UK that was done in two stages (a) in 2017 before the pandemic then (b) again in 2023, after the pandemic found that Functional Dyspepsia rose almost 44% (from 8% to 12%), and IBS increased 28% (from 5% to 6%) after the pandemic. It was also found that Functional Dyspepsia and IBS were often associated with people experiencing long-COVID, or diagnosed with anxiety disorder, or depression.

The Role of the Gut-Brain Axis

Functional Dyspepsia is sometimes referred to as having a “nervous stomach” because of the known interaction between the gut and the brain, along what is called the gut-brain axis. The gut-brain axis involves the vagus nerve, which is the longest nerve in the human body and which connects the brain to the organs, including the stomach, intestines, heart, and lungs.

Since symptoms of Functional Dyspepsia and some cases of IBS are more pronounced when the individuals are under stress, interventions may not only include dietary modifications, but may also include behavior interventions that can help relax the gut by affecting the vagus nerve.

Symptoms Vary Between Individuals

Individuals with Functional Dyspepsia may experience some symptoms, but not others, so dietary treatment must be individualized for each person, and some of the interventions used may be similar to those used for other functional disorders, such as IBS, or for digestive disorders such as Gastro-Esophageal Reflux Disorder (GERD), hiatus hernia, or Small Intestinal Bacterial Overgrowth (SIBO), or interventions that are unique to Functional Dyspepsia.

For example, addressing the symptom of bloating may involve the use of a low-FODMAP diet implemented over three stages, which is also used in some individuals with Irritable Bowel Syndrome (IBS), depending on which foods are causing the symptoms.

If acid reflux is one of the symptoms that people are experiencing, dietary interventions and lifestyle interventions may be similar to those used in Gastro-Esophageal Reflux Disorder (GERD), or to help decrease stomach pain, dietary recommendations may involve reducing irritants such as spices, alcohol, coffee, and caffeine.

Role of Behaviour Interventions in Functional Dyspepsia

Since Functional Dyspepsia (and sometimes IBS, as well) involves gut-brain interaction, there are some behavioral interventions that are often used, such as specific types of breathing exercises that affect the vagus nerve, help relax the gut, thus minimizing symptoms.

Clinical Application

In clinical practice, I will recommend that a client consult their doctor to be evaluated for Functional Dyspepsia when their symptoms seem sufficiently different than what is seen with IBS. On occasion, I am referred a client who has been diagnosed with functional dyspepsia, and sometimes I will recommend that people take an add-on nutrition education about Functional Dyspepsia as a fourth session to their IBS Package, or Comprehensive Dietary Package, especially when they have other conditions that contribute to vagus nerve involvement, slow motility, and/or increased anxiety.

Some Final Thoughts

Functional disorders like Functional Dyspepsia or IBS are diagnosed based on symptoms, rather than lab tests, because they don’t involve a structural or biological abnormality. As with IBS, a diagnosis of Functional Dyspepsia is made by a doctor after ruling out disease states or biological causes. Just as the diagnosis of Functional Dyspepsia is made based on symptoms, so too is the determination of which dietary modifications will be most appropriate.

More Info?

Learn about me and how I can help support you with dietary changes related to Functional Dyspepsia or IBS. View my Irritable Bowel Syndrome (IBS) Package, to which a Functional Dyspepsia add-on can be added.

To your good health!

Joy

You can follow me on:

Twitter: https://twitter.com/jyerdile
Facebook: https://www.facebook.com/BetterByDesignNutrition/

Reference

  1. Palsson, Olafur et al. The Prevalence and Burden of Disorders of Gut-Brain Interaction (DGBI) before versus after the COVID-19 Pandemic, Clinical Gastroenterology and Hepatology, Volume 0, Issue 0. [https://doi.org/10.1016/j.cgh.2025.07.012]
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