Better Outcome in Covid-19 and T2D with Well-Controlled Blood Sugars

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Introduction

A study published in the journal Cell Metabolism has reported that people with type 2 diabetes (T2D) are at much greater risk of having a poor outcome in COVID-19 if they have poorly controlled blood glucose. This study analyzed data from over 7,300 people hospitalized in Hubei Province, China, specifically comparing those with well-controlled versus poorly controlled blood sugar levels.

Poor Outcomes in Uncontrolled Diabetes

Consistent with previous reviews, people admitted to the hospital with the virus and pre-existing T2D had poorer outcomes. These individuals required more medical interventions, including supplemental oxygen and ventilators, and had higher mortality rates (7.8%) compared to those without diabetes (2.7%).

Encouragingly, the study found that patients with T2D who maintained well-controlled blood glucose ranging between 3.9 to 10.0 mmol/L (70-180 mg/dl) had much lower death rates than those whose blood sugar exceeded 10.0 mmol/L.

A Sobering Clinical Finding

The findings highlight a dramatic difference in survival based on glycemic management. Almost 99% (98.9%) of those with well-controlled blood glucose survived COVID-19. Conversely, 11% of those with poorly controlled blood glucose died. This provides strong clinical evidence that better blood sugar control leads to significantly better outcomes during hospitalization.

Final Thoughts

Glycemic control is not just a long-term health goal; it is a critical factor in acute recovery from infectious disease. Managing your blood sugar is one of the most effective ways to support your immune health and improve clinical outcomes.

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References

  1. Zhu L, She GZ, Cheng X, et al. Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes. Cell Metab. 2020 Jun 2;31(6):1068-1077.e3. [https://doi.org/10.1016/j.cmet.2020.04.021]
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